Product Identification

Product Name

2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido-[5,4-d]pyrimidin

Synonyms

2,2',2'',2'''-[[4,8-Dipiperidinopyrimido(5,4-d)pyrimidine-2,6-diyl]dinitrilo]tetraethanol
2,6-Bis-(diethanolamino)-4,8-dipiperidino-pyrimido[5,4-d]pyrimidine
Ethanol, 2,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-

CAS

58-32-2

Formula

C24H40N8O4

Molecular Weight

504.63

EINECS

200-374-7

RTECS

KK7450000

RTECS Class

Drug; Mutagen; Human Data

Merck

12,3410

Beilstein/Gmelin

68373

Beilstein Reference

4-26-00-03840

Physical and Chemical Properties

Appearance

Yellow powder.

Melting Point

165 - 166

pKa/pKb

7.63 (pKb)

Heat Of Vaporization

122.9 kJ/mol

Usage

Coronary vasodilator drug; adenosine transport inhibitor; inhibitor of platelet aggregation.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed. Store in a cool dry place. Store in the dark. Store at -20 C

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

36/37/38

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Irritant. Irritating to eyes, respiratory system and skin. Target organ(s): Heart. Blood.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures. Sensitive to light.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.