Product Identification

Product Name

2,4,6-Trimethylpyridine

Synonyms

1H-Tetrazole, 5-phenyl-, barium salt
2,4,6-Trimethylpyridine
Barium 5-phenyl-2,3,4-triaza-1-azanidacyclopenta-2,4-diene
sym-Collidine

CAS

55719-88-5

CAS

108-75-8

Formula

C14H10BaN8

Formula

C8H11N

Molecular Weight

121.18

Molecular Weight

429.63

EINECS

203-613-3

EINECS

259-775-0

RTECS

UU0970000

RTECS Class

Other

Merck

12,9848

Beilstein/Gmelin

107283

Beilstein/Gmelin

NA

Beilstein Reference

5-20-06-00093

EC Class

flammable, harmful, irritant

Physical and Chemical Properties

Appearance

Colorless liquid. Aromatic odor.

Solubility in water

Slightly soluble

Melting Point

-43

Boiling Point

171

Vapor Pressure

34 (80 C)

Density

0.9191 g/cm3 (20 C)

pKa/pKb

6.57 (pKb)

Partition Coefficient

1.88

Heat Of Vaporization

50.33 kJ/mol

Heat Of Combustion

-4689 kJ/mol

Usage

Chemical intermediate.

Vapor Density

4.2

Refractive Index

1.4953 (16.4 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Ingestion

Seek medical assistance.

Inhalation

TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.

Skin

Contact with molten substance may cause severe burns to skin and eyes. See Inhalation.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.

Eyes

See Inhalation.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Immediately flush with running water for at least 20 minutes.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

See Inhalation.

Inhalation

May cause liver and kidney damage. May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema.

Skin

Causes skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis.

Eyes

Causes eye irritation. May cause conjunctivitis.

Ingestion

Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause central nervous system effects and/or neurological effects.

Hazards

Contact with metals may evolve flammable hydrogen gas.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers.

EC Risk Phrase

R 10 21/22 36/37/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

1564

UN (DOT)

1992

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Overexposure may cause delayed kidney injury. Chronic ingestion may cause liver damage. Prolonged or repeated eye contact may cause conjunctivitis. Chronic ingestion may cause neurological symptoms.

Fire Fighting Measures

Flash Point

55

Fire Fighting

Extinguish using agent most appropriate for surrounding fire.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.

Upper exp. limit

8.9

Lower exp. limit

1

Fire Potential

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation.

Small spills/leaks

ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Stability and Reactivity

Disposal Code

5

Stability

No data.

Incompatibilities

Oxidizing agents

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1564

UN Number

1992

Hazard Class

3

Hazard Class

6.1

Packing Group

I; II; III

Packing Group

II; III

HS Code

2933 39 99