Product Identification

Product Name

(+/-)-Ofloxacin

Synonyms

7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10- (4-methyl-1-piperazinyl)-7-oxo-, (+-)
9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
9-Fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
HOE-280
Oflocet
Tarivid

CAS

82419-36-1

Formula

C18H20FN3O4

Molecular Weight

361.37

RTECS

UU8815500

Merck

12,6865

Beilstein/Gmelin

3657947

Physical and Chemical Properties

Solubility in water

Insoluble

Vapor Pressure

6.7E-14 (25 C)

Density

1.48 g/cm3 (20 C)

pKa/pKb

5.23 (pKa)

Partition Coefficient

1.61

Usage

Antibiotic.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C.

Exposure Controls/Personal Protection

Personal Protection

Protective work clothing. Chemical protective gloves. Safety glasses or goggles.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.

Exposure Effects

May cause irritation of the eyes, skin, mucous membranes and upper respiratory tract. May be harmful if inhaled, ingested or absorbed through the skin.

Fire Fighting Measures

Fire Fighting

Extinguish with carbon dioxide, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. Wear self-contained respirator. Wear fully protective impervious suit.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable if stored as directed..

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.

Hazards Identification

EC Safety Phrase

S: 22 24/25