Product Identification

Product Name

N-Phthaloylglycine

Synonyms

(1,3-Dioxo-1,3-dihydroisoindol-2-yl)acetic acid
1,3-Dihydro-1,3-dioxo-2H-isoindole-2-acetic acid
1,3-Dioxo-2-isoindolineacetic acid
2-Phthalimidoacetic acid
N-(2-Hydroxy-2-oxoethyl)phthalimide
N-(Carboxymethyl)phthalimide

CAS

4702-13-0

Formula

C10H7NO4

Molecular Weight

205.16

EINECS

225-177-3

RTECS

NR3439000

RTECS Class

Reproductive Effector

Beilstein/Gmelin

184174

Beilstein Reference

5-21-10-00430

Physical and Chemical Properties

Appearance

Slightly cream colored, almost odorless powder.

Solubility in water

Very soluble

Melting Point

199 - 202

Boiling Point

454

Density

1.45 g/cm3

pKa/pKb

3.61 (pKa)

Partition Coefficient

.25

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use. Refrigerator (approx 4 C).

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear chemical goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

The toxicological properties of this material have not been investigated.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Irritating and toxic fumes and gases.

Hazards Identification

EC Safety Phrase

S 22 24/25