Product Identification

Product Name

Dipropylene glycol monomethyl ether

Synonyms

(2-Methoxymethylethoxy)propanol
2-(2-Methoxypropoxy)propan-1-ol
Dipropylene glycol monomethyl ether
Dowanol 50b

CAS

34590-94-8

Formula

C7H16O3

Molecular Weight

148.19999999999999

EINECS

252-104-2

RTECS

JM1575000

RTECS Class

Primary Irritant

Merck

12,3407

Beilstein/Gmelin

NA

Physical and Chemical Properties

Appearance

Clear colorless liquid with a mild ethereal odor in moderate concentrations. May be a lachrymator as is the chemically related propylene glycol monomethyl ether.

Solubility in water

Miscible

Melting Point

-80

Boiling Point

190

Vapor Pressure

0.4 (25 C)

Density

0.951 g/cm3 (20 C)

Usage

In manufacture of various cosmetics.

Saturation Concentration

0.05% (500 ppm) at 25 C (calculated)

Vapor Density

5.11

Refractive Index

1.419 (25 C)

First Aid Measures

Ingestion

Treatment is symptomatic and supportive. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage

In general, toxic materials or that can decompose into toxic components should be stored in cool ventilated place, out of sun, away from fire hazard. Substance must be periodically inspected and monitored. Incompatible materials should be isolated.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Dipropylene glycol has little vapor hazard at ordinary temperatures.

Skin

Dry skin. Defats the skin. See inhalation. May be absorbed through the skin.

Eyes

Redness, pain.

Hazards

Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection

Protective gloves and clothing. Safety goggles.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

CNS depression was reported in dogs given 6 ml/kg iv. No toxicity was noted when 5 ml/kg was given orally.

Exposure limit(s)

TLV: 100 ppm; 606 mg/m3 (skin) (ACGIH 1991-1992). OSHA PEL: TWA 100 ppm (600 mg/m3) skin NIOSH REL: TWA 100 ppm (600 mg/m3) ST 150 ppm (900 mg/m3) skin NIOSH IDLH: 600 ppm

Poison Class

5

Fire Fighting Measures

Flash Point

79

Autoignition

205

Fire Fighting

Extinguish with dry chemical, alcohol foam, or carbon dioxide. Cool exposed containers with water.

Upper exp. limit

14

Lower exp. limit

1.1

Fire Potential

This material is combustible.

Accidental Release Measures

Small spills/leaks

Stop discharge if possible. Call fire department. Avoid contact with liquid. Isolate and remove discharged material. Notify local health and pollution control agencies. Evacuate areas. Should be removed. Chemical and physical treatment. Effect of low concentrations on aquatic life is unknown. May be dangerous if it enters water intakes. Notify local health and wildlife officials. Notify operators of nearby water intakes.

Stability and Reactivity

Disposal Code

1

Incompatibilities

May react violently with strong oxidizing agents.

Stability

Volatile.

Transport Information

HS Code

2909 49 19