Product Identification

Product Name

2-Bromo-1-(4-fluorophenyl)ethan-1-one

Synonyms

1-(4-Fluorophenyl)-2-bromoethanone
2-Bromo-1-(4-fluorophenyl)ethanone
2-Bromo-p-fluoroacetophenone
Bromomethyl 4-fluorophenyl ketoxime
p-Fluorophenacyl bromide

CAS

403-29-2

Formula

C8H6BrFO

Molecular Weight

217.03

EINECS

206-955-1

Beilstein/Gmelin

637863

Beilstein Reference

4-07-00-00650

Physical and Chemical Properties

Appearance

Off white crystals.

Solubility in water

Sparomg;u sp;ib;e

Melting Point

49

Boiling Point

82 (0.4 torr)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Eyes

Get medical aid. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Store protected from moisture.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Discard contaminated shoes. Keep from contact with moist air and steam.

Hazards Identification

Ingestion

May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause headache. May cause nausea and vomiting.

Inhalation

May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.

Skin

Causes skin burns. Vesicant. May cause eczematous dermatitis with swelling and vesiculation.

Eyes

Causes eye burns. Lachrymator.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

1759

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures

Flash Point

> 110

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Do not get water inside containers.

Stability and Reactivity

Incompatibilities

Moisture, strong bases, strong oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride, hydrogen bromide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1759

Hazard Class

8

Packing Group

I; II; III