Product Identification

Product Name

4',7-Dihydroxyisoflavone

Synonyms

7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
7-Hydroxy-3-(4-hydroxyphenyl)chromen-4-one

CAS

486-66-8

Formula

C15H10O4

Molecular Weight

254.24

EINECS

207-635-4

RTECS

DJ3100040

RTECS Class

Drug

Merck

13,2829

Beilstein/Gmelin

231523

Beilstein Reference

5-18-04-00089

Physical and Chemical Properties

Appearance

Almost white solid.

Solubility in water

Insoluble

Melting Point

212 - 214

Boiling Point

513

Vapor Pressure

4E-11 (25 C)

pKa/pKb

7.54

Partition Coefficient

2.97

Heat Of Vaporization

81.4 kJ/mol

Usage

Used to evaluate time-resolved fluoroimmunoassay for determination of daidzein in plasma (serum).

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Deep freeze (below -20 C).

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. May be harmful if swallowed. May cause headache, drowsiness, and

Inhalation

Causes respiratory tract irritation. May be harmful if inhaled. Exposure to high concentrations may cause narcosis.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

201

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Sterk oxyderend middel.

Decomposition

Carbon monoxide, carbon dioxide.