Product Identification

Product Name

Mesitylenesulfonyl chloride

Synonyms

2,4,6-Trimethylbenzenesulfonyl chloride
2,4,6-Trimethylphenylsulfonyl chloride
2-Hydroxy-1-ethanethiol
2-Mercaptoethanol
2-Mesitylenesulfonyl chloride
2-Sulfanylethanol
Monothioethyleneglycol

CAS

60-24-2

CAS

773-64-8

Formula

C2H6OS

Formula

C9H11ClO2S

Molecular Weight

78.13

Molecular Weight

218.7

EINECS

200-464-6

EINECS

212-257-8

RTECS

DB8930000

RTECS

KL5600000

RTECS Class

Mutagen; Primary Irritant

RTECS Class

Other

Merck

13,5894

Beilstein/Gmelin

1107601

Beilstein/Gmelin

773648

Beilstein Reference

3-11-00-00346

Beilstein Reference

4-01-00-02428

EC Class

toxic, corrosive, dangerous for the environment

EC Class

corrosive

Physical and Chemical Properties

Appearance

Colorless liquid with a faint characteristic odor.

Appearance

Slightly beige solid.

Solubility in water

Soluble

Solubility in water

Insoluble

Melting Point

53 - 56

Melting Point

-100

Boiling Point

150 (20 torr)

Boiling Point

157

Vapor Pressure

1.0 (25 C)

Density

1.1317 g/cm3 (0 C)

pKa/pKb

9.74 (pKa)

Partition Coefficient

-.326

Heat Of Vaporization

45.9 kJ/mol

Usage

Solvent for dyestuffs, intermediate for producing dyestuffs, pharmaceuticals, rubber chemicals, flotation agents, insecticides, plasticizers, water-soluble reducing agent, biochemical reagent, pvc stabilizers, agricultural chemicals, textile auxiliary.

Vapor Density

7.5

Saturation Concentration

81600 ppm (8.2%) at 20 C

Vapor Density

2.7

Odor threshold

0.38 mg/m3

Refractive Index

1.4963 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Ingestion

Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause muscle paralysis, respiratory failure, and possible death.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.

Inhalation

Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause dyspnea (difficult breathing from shortness of breath). Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis, cold extremities and rapid pulse. Mercaptans may cause nausea and headache.

Skin

May be fatal if absorbed through the skin. Causes irritation with burning pain, itching, and redness.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Eyes

May cause severe eye irritation. May result in corneal injury.

Eyes

Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Storage

Keep container closed when not in use. Corrosives area. Refrigerator (approx 4 C).

Handling

Keep container tightly closed. Do not get on skin or in eyes. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Ingestion

May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns.

Inhalation

May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract.

Skin

May cause severe irritation and possible burns.

Eyes

Contact with eyes may cause severe irritation, and possible eye burns.

Hazards

Contact with metals may evolve flammable hydrogen gas.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

EC Risk Phrase

R 20/22 24 34 51/53

EC Risk Phrase

R 34

EC Safety Phrase

S 26 36/37/39 45

EC Safety Phrase

S 26 36/37/39 45 61

UN (DOT)

1759

UN (DOT)

2966

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Exposure Effects

Prolonged or repeated skin contact may cause defatting and dermatitis. Repeated or prolonged exposure may cause CNS stimulation.

Exposure limit(s)

OEL-RUSSIA:STEL 1 mg/m3

Poison Class

3

Fire Fighting Measures

Flash Point

>112

Flash Point

68

Autoignition

295

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible Liquid. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Do NOT use water directly on fire. Use foam, dry chemical, or carbon dioxide.

Upper exp. limit

18

Lower exp. limit

2.3

Fire Potential

May burn but does not ignite readily.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation.

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

11

Disposal Code

6

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizers, calcium hypochlorite, metals, strong acids, caustics, aliphatic amines, isocyanates.

Decomposition

Hydrogen chloride, carbon monoxide, oxides of sulfur, carbon dioxide.

Decomposition

Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2966

UN Number

1759

Hazard Class

6.1

Hazard Class

8

Packing Group

I; II; III

Packing Group

II

HS Code

2904 90 20

HS Code

2930 90 70