Product Identification

Product Name

Hexahydro-1-methyl-1H-1,4-diazepine

Synonyms

1-Methyl-[1,4]diazepan
1-Methyl-2,3,4,5,6,7-hexahydro-1H-1,4-diazepine
1-Methylperhydro-1,4-diazepine
Hexahydro-1-methyl-1,4-diazepine
N-Methyl-1,4-diazacycloheptane
N-Methylhomopiperazine

CAS

4318-37-0

Formula

C6H14N2

Molecular Weight

114.19

Beilstein Reference

5-23-03-00241

Physical and Chemical Properties

Appearance

Clear, colorless liquid.

Solubility in water

77 g/L (25 C)

Melting Point

33

Boiling Point

164

Vapor Pressure

2.8 (25 C)

Density

0.918 g/cm3 (25 C)

pKa/pKb

3.17 (pKb)

Partition Coefficient

.21

Heat Of Vaporization

39.41 kJ/mol

Refractive Index

1.477 (20 C)

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep container tightly closed.

Hazards Identification

Inhalation

Material is extremely destructive to the tissue of the mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes burns. May be harmful if absorbed through the skin.

Eyes

Causes burns.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

10 22 34

EC Safety Phrase

16 26 27 36/37/39 45

UN (DOT)

2920

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing. Faceshield (8 inch minimum).

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.

Exposure Effects

Symptoms of exposure may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Inhalation may result in spasm, inflammation and edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema. Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin.

Fire Fighting Measures

Flash Point

45

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Potential

Combustible liquid.

Accidental Release Measures

Small spills/leaks

Cover with dry lime or soda ash, pick up, keep in a closed container, and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Oxides of carbon, oxides of nitrogen.

Transport Information

UN Number

2920

Hazard Class

8

Packing Group

II