Product Identification

Product Name

Sulfadimethoxine

Synonyms

2,4-Dimethoxy-6-sulfanilamido-1,3-pyrimidine
4-(p-Aminobenzenesulfonamido)-2,6-dimethoxypyrimidine
4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
4-Sulfa-2,6-dimethoxypyrimidine
6-Sulfanilamido-2,4-dimethoxy-1,3-diazine
Dimethoxysulfadiazine

CAS

122-11-2

Formula

C12H14N4O4S

Molecular Weight

310.33

EINECS

204-523-7

RTECS

WO9030000

RTECS Class

Drug; Reproductive Effector

Merck

12,9073

Beilstein/Gmelin

306856

Beilstein Reference

5-25-13-00290

Physical and Chemical Properties

Appearance

White, almost tasteless and odorless powder.

Solubility in water

Insoluble

Melting Point

202 - 204

Boiling Point

549

Vapor Pressure

4E-12 (25 C)

Density

1.654 g/cm3 (20 C)

pKa/pKb

6.21 (pKa)

Heat Of Vaporization

82.8 kJ/mol

Usage

Veternary antibiotic effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

36/37/38 43

EC Safety Phrase

26 36/37

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Irritant. Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact. Target organ(s): Blood. Kidneys.

Fire Fighting Measures

Flash Point

286

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.