Product Identification

Product Name

8,13,13b,14-Tetrahydro-14-methylindolo[2'3'-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one

Synonyms

Indol(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-, (S)-
Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13,13b,14-tetrahydro-14-methyl-

CAS

518-17-2

Formula

C19H17N3O

Molecular Weight

303.36

Merck

12,3954

Physical and Chemical Properties

Appearance

Yellow solid.

Solubility in water

Insoluble

Melting Point

263 - 265

Vapor Pressure

3.2E-13 (25 C)

Density

1.39 g/cm3 (20 C)

pKa/pKb

11.86 (pKb)

Partition Coefficient

1.45

Usage

Has been shown to reduce fat uptake in mouse studies.

Handling and Storage

Storage

Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above -20 C.

Hazards Identification

Inhalation

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.

Skin

In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.

Eyes

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.

Ingestion

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.

Exposure Controls/Personal Protection

Personal Protection

Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.

Fire Fighting Measures

Fire Fighting

Extinguishing agents - SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear.

Fire Potential

May be combustible at high temperature.

Accidental Release Measures

Small spills/leaks

Use appropriate tools to put the spilled solid in a convenient waste disposal container.