Product Identification

Product Name

Warfarin sodium

Synonyms

2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, sodium salt
Coumadin sodium
Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, sodium salt
Zoocoumarin sodium salt

CAS

129-06-6

Formula

C19H16NaO4

Molecular Weight

331.32

EINECS

204-929-4

RTECS

GN4725000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data

Beilstein/Gmelin

5469050

Physical and Chemical Properties

Appearance

Slightly bitter crystalline powder. Odorless.

Heat Of Vaporization

Usage

Rodenticide.

First Aid Measures

Ingestion

Give water and induce vomiting. Never give anthing to an unconscious person. Obtain medical attention.

Inhalation

Remove to fresh air. Give CPR and/or oxygen if required.

Skin

Wash with soap and water.

Eyes

Flush with water for 15 minutes.

Handling and Storage

Storage

Store at away from heat and open flame. Do not store near feeds and foodstuffs and keep away from children, domestic animals, pets, or wildlife.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

This material is highly toxic orally in humans. Long term overexposure may cause susceptibility to bruising, longer blod clotting times, blood in the stool and urine. Blotches on the skin.

Skin

See inhalation.

Eyes

See inhalation

Ingestion

See inhalation.

Hazards

When heated to decomposition, it emits toxic fumes of sodium oxide.

Exposure Controls/Personal Protection

Personal Protection

Use safety glasses and full face shield, Neoprene or Tyvek gloves, apron, boots and/or whole body suit.

Respirators

Wear NIOSH/<SHA pproved air purifying respirator/positive pressure air-supplied respirator.

Exposure Effects

Warfarin has been established as a human teratogen, because it causes birth defects in the offspring of women receiving clinical doses of the compound during any trimester of pregnancy.

Fire Fighting Measures

Fire Fighting

Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site. Move container from fire area if you can do it without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Extinguish fires with dry chemical, carbon dioxide, water spray, fog, or foam.

Accidental Release Measures

Small spills/leaks

Do not touch spilled material; stop leak if you can do it without risk. Use water spray to reduce vapors. For small spills, take up with sand or other noncombustible absorbent material and place into containers for later disposal. For small dry spills, with clean shovel place material into clean, dry container and cover; move containers from spill area. For large spills, dike far ahead of spill for later disposal.

Stability and Reactivity

Stability

Contact with strong oxidizers may cause fires and explosions.