Product Identification

Product Name

Cycloleucine

Synonyms

1-Amino-1-cyclopentanecarboxylic acid
1-Aminocyclopentane-1-carboxylic acid
1-Aminocyclopentanecarboxylic acid

CAS

52-52-8

Formula

C6H11NO2

Molecular Weight

129.16

EINECS

200-144-6

RTECS

GY2625000

RTECS Class

Drug; Mutagen; Human Data

Merck

13,2763

Beilstein/Gmelin

636626

Beilstein Reference

4-14-00-00974

Physical and Chemical Properties

Appearance

White flakes

Solubility in water

Very soluble

Melting Point

163

Boiling Point

254

pKa/pKb

2.38 (pKa)

Partition Coefficient

-.03

Usage

Biological testing materials for immunosuppressive properties in mice, for amino acid transport studies.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

Harmful if swallowed. May cause nausea and vomiting.

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 22 36/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents; strong acids; strong bases.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III