Product Identification

Product Name

Folpet

Synonyms

2-((Trichloromethyl)thio)-1H-isoindole-1,3(2H)-dione
2-(Trichloromethylsulfanyl)isoindole-1,3-dione
Acryptan
N-(Trichloromethylthio)phthalimide
Orthophaltan

CAS

133-07-3

Formula

C9H4Cl3NO2S

Molecular Weight

296.56

EINECS

205-088-6

RTECS

TI5685000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector

Merck

12,4255

Beilstein/Gmelin

193373

Beilstein Reference

5-21-11-00118

EC Index Number

613-045-00-1

EC Class

Carcinogenic Category 3; Harmful; Irritant; Sensitising; Dangerous for the Environment

Physical and Chemical Properties

Appearance

White crystals.

Solubility in water

Insoluble

Melting Point

442 - 446

Vapor Pressure

<0.0001

Density

1.78 g/cm3 (25 C)

Partition Coefficient

2.85

Usage

Fungicide.

First Aid Measures

Ingestion

Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Remove contaminated clothing. Wash exposed area with soap and water. If symptoms persist, seek medical attention. Launder clothing before reuse.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Folpet is a respiratory tract irritant and can produce occupational asthma.

Skin

Irritant and allergic contact dermatitis have been reported with captan, folpet, and captafol.

Eyes

Folpet is an irritant of the eyes and mucous membranes.

Ingestion

Nausea, vomiting, and diarrhea may follow ingestion.

Exposure Controls/Personal Protection

Personal Protection

Goggles or a face shield.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

The phthalimide fungicides contain the phthalimide moiety in common with phthalidomide, a known human teratogen. Captan has been teratogenic, fetotoxic, and/or embryotoxic in a variety of rodent species and caused stillbirths in dogs. Folpet was teratogenic in rabbits, chicks, and hamsters. Captafol has been embryo- or fetotoxic in experimental animals. <br>Captan, folpet, and captafol have all induced testicular degeneration in laboratory animals.

Poison Class

4

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

Stability and Reactivity

Incompatibilities

Strong oxidizing agents.

Stability

Virtually non-volatile; stable when dry, but slowly hydrolyzes in water at ordinary temperature, rapidly @ high temperature or under alkaline conditions.

Decomposition

When heated to decomposition it emits very toxic fumes of hydrogen chloride, nitrogen oxides and sulfur oxides.