Product Identification

Product Name

3beta-hydroxy-5-cholestene

Synonyms

Cholest-5-en-3beta-ol

CAS

57-88-5

Formula

C27H46O

Molecular Weight

386.66

EINECS

200-353-2

RTECS

FZ8400000

RTECS Class

Tumorigen; Mutagen; Reproductive Effector; Natural Product

Merck

13,2221

Beilstein/Gmelin

1915888

Beilstein Reference

4-06-00-04000

Physical and Chemical Properties

Appearance

White, near odorless powder.

Solubility in water

Insoluble

Melting Point

147

Boiling Point

360

Vapor Pressure

0.002 (137 C)

Density

1.046 g/cm3

Partition Coefficient

9.85

Heat Of Vaporization

85.9 kJ/mol

Usage

Pharmaceutic aid (emulsifying agent).

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container. Keep from contact with oxidizing materials.

Handling

Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

Ingestion of large amounts may cause gastrointestinal irritation. Expected to be a low ingestion hazard.

Inhalation

May cause respiratory tract irritation. Low hazard for usual industrial handling.

Skin

May cause skin irritation. Low hazard for usual industrial handling.

Eyes

May cause eye irritation. Dust may cause mechanical irritation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

-

Fire Fighting Measures

Flash Point

209

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode in the heat of a fire. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.

Stability and Reactivity

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, irritating and toxic gases, carbon dioxide.