Product Identification

Product Name

(1R,2S,5R)-(-)-Menthol

Synonyms

(-)-Menthyl alcohol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1R,2S,5R)-(-)-Menthol
(1R,2S,5R)-5-Methyl-2-propan-2-ylcyclohexan-1-ol
L-p-Menthan-3-ol

CAS

2216-51-5

Formula

C10H20O

Molecular Weight

156.27000000000001

EINECS

218-690-9

RTECS

OT0700000

RTECS Class

Mutagen; Natural Product; Primary Irritant

Merck

13,5861

Beilstein/Gmelin

1902293

Beilstein Reference

4-06-00-00150

EC Class

irritant

Physical and Chemical Properties

Appearance

Crystals or granules. Peppermint odor.

Solubility in water

0.4 g/L

Melting Point

41 - 44

Boiling Point

212

Vapor Pressure

0.8 (25 C)

Density

0.89 g/cm3 (15 C)

Partition Coefficient

3.3

Heat Of Vaporization

56.92 kJ/mol

Heat Of Combustion

-6319 kJ/mol

Usage

Medication: topical antipruritic, medication (vet): has been used as a mild local anesthetic, antiseptic & internally as a carminative & gastric sedative menthol.

Refractive Index

1.46 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Use with adequate ventilation. Use only in a chemical fume hood.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Eyes

Causes eye irritation. May cause conjunctivitis and corneal inflammation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

EC Risk Phrase

R 37/38 41

EC Safety Phrase

S 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Poison Class

4 (Substances and products that must be considered harmful)

Fire Fighting Measures

Flash Point

96

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Water may be ineffective. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong oxidizing agents, phenols, potassium permanganate, chromium trioxide, chloral hydrate, thymol, pyrogallol, resorcinol, camphor, butylchloral hydrate, betanaphthol, exalgine.

Decomposition

Carbon monoxide, carbon dioxide, acrid smoke and fumes.

Transport Information

HS Code

2906 11 00