Product Identification

Product Name

Tetramethyllead

Synonyms

Lead tetramethyl
Tetramethyl plumbane

CAS

75-74-1

Formula

C4H12Pb

Molecular Weight

267.35000000000002

EINECS

200-897-0

RTECS

TP4725000

RTECS Class

Organometallic; Reproductive Effector

Beilstein/Gmelin

3902986

Beilstein Reference

4-04-00-04348

Physical and Chemical Properties

Appearance

Colorless liquid, dyed red, orange or blue. Has a slight musty odor.

Solubility in water

0.02 g/L

Melting Point

-27.5

Boiling Point

375

Vapor Pressure

18 (25 C)

Density

2.034 g/cm3 (0 C)

Partition Coefficient

2.98

Heat Of Vaporization

34.5 kJ/mol

Heat Of Combustion

-3285 kJ/mol

Usage

Antiknock additive for gasolines.

Vapor Density

6.5

Refractive Index

1.5068 (20 C)

First Aid Measures

Ingestion

The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Protect against physical damage. Outside or detached storage is preferred. Inside storage should be in a standard flammable liquids storage room or cabinet. Separate from halogens and other oxidizing agents. Protect against electrical sparks, open flames, or other heat sources. Tank storage should be protected by dikes, diversion walls or ditches and be sprinkled.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Convulsions. Dizziness. Headache. Nausea. Unconsciousness. Hallucination. Symptoms may be delayed.

Skin

Irritation and pain. May be absorbed through the skin.

Eyes

Redness, pain.

Ingestion

Abdominal pain. Burning sensation. Diarrhoea. Dullness.

Hazards

Thermal decomposition is likely to take the form of vapors at the surface. Rapid decomposition will cause container to explode. Dangerous fire hazard when exposed to heat, flame, or oxidizers. Toxic gases are generated in fire. Avoid strong oxidizers such as sulfuryl chloride or potassium permanganate. Avoid fire, heat, physical damage, and strong oxidizers. Starts to decompose at about 212F. If confined, may explode or detonate at high temperatures.

EC Risk Phrase

R 26/27/28 33 61

EC Safety Phrase

S 45 53

UN (DOT)

1649

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate personal protective clothing to prevent skin contact. Wear appropriate eye protection to prevent eye contact. Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure.

Respirators

Any self contained breathing apparatus with a full facepiece and operated in a pressure demand or other positive pressure mode or any supplied air respirator with a full facepiece and operated in a pressure demand or other positive pressure mode in combination with an auxiliary self contained breathing apparatus operated in pressure demand or other positive pressure mode.

Exposure Effects

Irregular breathing, abnormally low blood pressure, fever, or reduced body temperature have been reported. Clinical neurologic effects of organolead intoxication can be divided into mild, moderate, and severe. 1. Mild - anxiety, irritability, insomnia, lurid dreams, vomiting, metallic taste, pallor, cerebellar ataxia, and diarrhea. 2. Moderate - disorientation, hyperexcitability, tremors, chorea, bradycardia, hypotension, and hypothermia. 3. Severe - delusions, hallucinations, mania, convulsions, cerebral edema, coma, and death. Tetramethyl lead is fetotoxic, but not teratogenic, in rats. <br>&nbsp;&nbsp;&nbsp;1. The offspring of heavy gasoline sniffers have had severe mental retardation. <br>&nbsp;&nbsp;&nbsp;2. Organolead has reduced libido, potency, and spermatogenesis in occupationally exposed men.

Exposure limit(s)

NIOSH REL: TWA 0.075 mg/m3 [skin] OSHA PEL: TWA 0.075 mg/m3 [skin] 40 mg/m3 (as Pb)

Poison Class

1

Fire Fighting Measures

Flash Point

27

Fire Fighting

Use water to keep fire exposed containers cool. If leak or spill has not ignited, use water spray to disperse vapors or flush spill. For massive fire in cargo area, use unmanned hose holder or monitor nozzle; if this is impossible withdraw from area and let fire burn.On fires in which containers are not exposed, use water spray, dry chemical, foam or carbon dioxide.

Lower exp. limit

1.8

Fire Potential

Flammable liquid and vapor.

Accidental Release Measures

Small spills/leaks

Caution : Flammable liquid. Avoid sources of extreme heat or ignition including sparks or fire. When burned, toxic fumes of lead oxide will be emitted. Do not touch spilled material; stop leak if you can do it without risk. Use water spray to reduce vapors. Small spills: take up with sand or other non-combustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal.

Stability and Reactivity

Stability

Reactive under confinement, extreme caution.

Incompatibilities

Sensitive to heat Can react with strong oxidizers.

Decomposition

Temperatures above 100 C (212 F) cause decomposition and development of pressure that may cause containers to burst. When heated to decomposition it emits toxic fumes of lead.

Combustion Products

Lead fumes and carbon monoxide

Transport Information

UN Number

1649

Hazard Class

6.1

Packing Group

I