Product Identification

Product Name

RWJ-17021

Synonyms

2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
Topimax
Topiramic acid

CAS

97240-79-4

Formula

C12H21NO8S

Molecular Weight

339.37

RTECS

LS7083000

Merck

12,9686

Beilstein/Gmelin

5988957

Physical and Chemical Properties

Boiling Point

421

Usage

An anticonvulsant drug. Used to treat epilepsy in both children and adults.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Store at 2 - 8 C. Keep container tightly closed.

Hazards Identification

Ingestion

May be harmful if swallowed.

Inhalation

May be harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes irritation.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

36/37/38

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator.

Fire Fighting Measures

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable if stored as directed.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.