Product Identification

Product Name

Flurbiprofen

Synonyms

2-(2-Fluoro-4-biphenylyl)propionic acid
2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid
2-Fluoro-alpha-methyl-4-biphenylacetic acid
3-Fluoro-4-phenylhydratropic acid
BTS-18322

CAS

5104-49-4

Formula

C15H13FO2

Molecular Weight

244.27

EINECS

225-827-6

RTECS

DU8341000

RTECS Class

Drug; Reproductive Effector; Human Data

Merck

12,4234

Beilstein/Gmelin

2054451

Beilstein Reference

6-06

Physical and Chemical Properties

Solubility in water

ll mg/L (25 C)

Melting Point

113 - 114

Boiling Point

376

Vapor Pressure

3E-6 (25 C)

Density

1.279 g/cm3 (25 C)

pKa/pKb

4.14 (pKa)

Heat Of Vaporization

65.8 kJ/mol

Usage

Non-steroidal anti-inflammatory agent with antifungal activity.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

Toxic if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

25

EC Safety Phrase

36/37/39 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Toxic. Toxic if swallowed. Possible sensitizer. Target organ(s): Kidneys.

Fire Fighting Measures

Flash Point

181

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Hydrogen fluoride.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

II