Product Identification

Product Name

2'-Deoxy-5-iodouridine

Synonyms

(+)-5-Iodo-2'-deoxyuridine
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
Herplex
Idoxuridine

CAS

54-42-2

Formula

C9H11IN2O5

Molecular Weight

354.1

EINECS

200-207-8

RTECS

YU7700000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector

Merck

12,4934

Beilstein/Gmelin

30397

Beilstein Reference

4-24-00-01235

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

2.0 mg/ml

Melting Point

164 - 166

Boiling Point

531

pKa/pKb

8.25(at 25℃) (pKa)

Partition Coefficient

-.63

Usage

Used as an antiviral agent.

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.

Hazards Identification

Ingestion

Harmful if swallowed. May cause irritation of the digestive tract.

Inhalation

Harmful if inhaled. May cause respiratory tract irritation. Causes irritation of mucous membrane.

Skin

May cause skin irritation. Harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Autoignition

350

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen iodide.