Product Identification

Product Name

alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-benzeneacetonitrile hydrochloride

Synonyms

Calan
Cordilox
D-365 hydrochloride
Finoptin
Iproveratril hydrochloride
Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride

CAS

152-11-4

Formula

C27H39ClN2O4

Molecular Weight

491.07

EINECS

205-800-5

RTECS

YV8320000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data

Beilstein/Gmelin

3647093

Physical and Chemical Properties

Appearance

odorless white powder

Melting Point

142 - 145

pKa/pKb

8.6(at 25℃) (pKa)

Partition Coefficient

.58

Usage

Blood pressure medication.

First Aid Measures

Ingestion

Get medical aid immediately. Wash mouth out with water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Refrigerator (approx 4 C).

Handling

Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. Poison by ingestion.

Inhalation

May cause respiratory tract irritation. Toxic if inhaled. May cause nausea, dizziness, and headache.

Skin

May cause skin irritation. Toxic in contact with skin.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Incompatibilities

Bases.

Stability

Stable under normal shipping and handling conditions.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.