Product Identification

Product Name

Diphenylnitrosamine

Synonyms

Curetard a
Delac j
Diphenyl n-Nitrosoamine
Diphenylnitrosamine
N,N-Diphenylnitrosamine
Vultrol

CAS

86-30-6

Formula

C12H10N2O

Molecular Weight

198.22

EINECS

201-663-0

RTECS

JJ9800000

RTECS Class

Tumorigen; Mutagen; Primary Irritant

Beilstein/Gmelin

909531

Beilstein Reference

4-16-00-00865

Physical and Chemical Properties

Appearance

Yellow to brown or orange powder or flakes or a black solid.

Solubility in water

10 mg/L (25 C)

Melting Point

63 - 65

Boiling Point

347

Vapor Pressure

6E-5 (25 C)

Density

1.251 g/cm3

Partition Coefficient

3.13

Heat Of Vaporization

59.1 kJ/mol

Heat Of Combustion

-6418 kJ/mol

Usage

An effective radical scavenger, and can be used to stabilize monomers, polymers, and petroleum products. In rubber processing, its major use is believed to be as an anti-scorching agent, or vulcanization retarder, during rubber compounding.

First Aid Measures

Ingestion

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

Inhalation

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.

Skin

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Storage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Pulmonary edema, congestion, and hemorrhagic areas have been reported.

Ingestion

Vomiting, gastrointestinal hemorrhage, and peritonitis have occurred.

Exposure Controls/Personal Protection

Personal Protection

Gloves which are impermeable should be worn. Dispensers of liquid detergent should be available. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, and disposable plastic aprons might provide additional protection. Protective clothing should be of distinctive color, as a reminder not to be worn outside the laboratory.

Respirators

Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).

Exposure Effects

Seizures, cerebral edema, headache, and malaise have been reported. Fetal death, fetotoxicity, and other teratogenic effects were observed in rat and mouse studies. Pre- and post-implantation mortality and abortion were observed in rats. Abnormal changes in sperm morphology were detected in mice.

Fire Fighting Measures

Flash Point

163

Fire Fighting

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity

Incompatibilities

Sensitive to moisture at elevated temperatures in strongly acidic solutions May react vigorously with oxidizing agents.

Stability

The nitrosamines are stable at neutral pH. Nitrosamines.