Product Identification

Product Name

4,4'-Methylenebisbenzeneamine

Synonyms

4,4'-Methylenebisbenzeneamine
4,4'-Methylenedianiline
4-[(4-Aminophenyl)methyl]aniline
Methylenebis(aniline)

CAS

101-77-9

Formula

C13H14N2

Molecular Weight

198.27

EINECS

202-974-4

RTECS

BY5425000

RTECS Class

Tumorigen; Mutagen; Human Data; Primary Irritant

Merck

13,3000

Beilstein/Gmelin

474706

Beilstein Reference

4-13-00-00390

EC Index Number

612-051-00-1

EC Class

Carcinogenic Category 2; Mutagenic Category 3; Toxic; Harmful; Sensitising; Dangerous for the Environment

Physical and Chemical Properties

Appearance

A tan flake or lump solid with a faint fishlike odor.

Solubility in water

Insoluble

Melting Point

91 - 92

Boiling Point

398

Vapor Pressure

1.5E-6 (25 C)

Density

1.15 g/cm3 (20 C)

pKa/pKb

8.68 kJ/mol

Partition Coefficient

1.59

Heat Of Vaporization

64.9 kJ/mol

Usage

Determination of tungsten & sulfates, as corrosion inhibitor, prepn of azo dyes.

Vapor Density

6.8

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.

Skin

May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.

Eyes

May cause eye irritation.

Ingestion

May cause irritation of the digestive tract. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

EC Risk Phrase

R 45 39/23/24/25 43 48/20/21 51/53 68

EC Safety Phrase

S 53 45 61

UN (DOT)

2651

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Prolonged exposure may cause anemia and methemoglobinemia, characterized by dizziness, drowsiness, headache, breath shortness, cyanosis, rapid heart rate and chocolate-brown colored blood. Repeated exposure may cause sensitization dermatitis. Effects may be delayed. Potential cancer hazard.

Exposure limit(s)

TLV: 0.1 ppm; 0.81 mg/m3 (A2) (skin) (ACGIH 1990-1991). OSHA PEL: 1910.1050 TWA 0.010 ppm ST 0.100 ppm NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen

Poison Class

1*

Fire Fighting Measures

Flash Point

221

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.

Fire Potential

May burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2651

Hazard Class

6.1

Packing Group

III