Product Identification

Product Name

4-Nitrophenol

Synonyms

4-Hydroxynitrobenzene
p-Nitrophenol

CAS

100-02-7

Formula

C6H5NO3

Molecular Weight

139.11000000000001

EINECS

202-811-7

RTECS

SM2275000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen

Merck

12,6718

Beilstein/Gmelin

1281877

Beilstein Reference

4-06-00-01279

EC Index Number

609-015-00-2

EC Class

Harmful; Danger of cumulative effects

Physical and Chemical Properties

Appearance

A white to light yellow crystalline solid.

Solubility in water

16 g/L

Melting Point

110 - 114

Boiling Point

279

Vapor Pressure

0.6 (120 C)

Density

1.236 g/cm3 (160 C)

pKa/pKb

7.15 (pKa)

Partition Coefficient

1.91

Heat Of Vaporization

56.2 kJ/mol

Heat Of Combustion

-2869 kJ/mol

Usage

As indicator in 0.1% Alcohol soln, ph range: 5.6 Colorless, 7.6 Yellow.

Vapor Density

1.244

Odor threshold

58.3 mg/L

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Call a poison control center.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Keep away from food and drinking water. Keep from contact with oxidizing materials.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid prolonged or repeated contact with skin. Wash clothing before reuse.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

May cause severe skin irritation.

Eyes

May cause severe eye irritation.

Ingestion

Harmful if swallowed. May cause central nervous system depression, kidney damage, and liver damage. May cause methemoglobinemia, cyanosis, convulsions, and death. May cause digestive tract disturbances.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 20/21/22 33

EC Safety Phrase

S 28

UN (DOT)

1663

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause liver and kidney damage.

Poison Class

2

Fire Fighting Measures

Flash Point

142

Autoignition

283

Fire Fighting

Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use foam, dry chemical, or carbon dioxide. Keep run-off water out of sewers and water sources.

Fire Potential

Slightly flammable. Combustible solid, may thermally decompose in absence of air.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal shipping and handling conditions.

Incompatibilities

Strong oxidizing agents; Strong bases; Diethyl phosphite

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Toxic oxides of nitrogen and fumes of unburned material may form in fires.

Transport Information

UN Number

1663

Hazard Class

6.1

Packing Group

III

HS Code

2908 90 00