Product Identification

Product Name

Ethylene glycol

Synonyms

1,2-Ethanediol
Ethane-1,2-diol
Monoethylene glycol

CAS

107-21-1

Formula

C2H6O2

Molecular Weight

62.07

EINECS

203-473-3

RTECS

KW2975000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant

Merck

13,3832

Beilstein/Gmelin

505945

Beilstein Reference

4-01-00-02369

EC Index Number

603-027-00-1

EC Class

Harmful

Physical and Chemical Properties

Appearance

Clear, colorless, syrupy liquid, hygroscopic.

Solubility in water

Miscible

Melting Point

-13

Boiling Point

195

Vapor Pressure

0.06 (20 C)

Density

1.115 g/cm3 (20 C)

pKa/pKb

14.22(at 25℃) (pKa)

Partition Coefficient

-1.36

Heat Of Vaporization

50.5 kJ/mol

Heat Of Combustion

-1036 kJ/mol

Usage

Automotive antifreeze, solvent, adjuvant.

Saturation Concentration

66 ppm at 20 C

Vapor Density

2.6

Odor threshold

Odorless

Refractive Index

1.43312 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

Vapor inhalation is generally not a problem unless heated or misted. Exposure to vapors over an extended time period has caused throat irritation and headache. May cause nausea, vomiting, dizziness and drowsiness. Pulmonary edema and central nervous system depression may also develop. When heated or misted, has produced rapid, involuntary eye movement and coma.

Skin

May cause skin irritation. Low hazard for usual industrial handling.

Eyes

Splashes may cause irritation, pain, eye damage.

Ingestion

Initial symptoms in massive dosage parallel alcohol intoxication, progressing to CNS depression, vomiting, headache, rapid respiratory and heart rate, lowered blood pressure, stupor, collapse, and unconsciousness with convulsions. Death from respiratory arrest or cardiovascular collapse may follow. Lethal dose in humans: 100 ml.

EC Risk Phrase

R 22

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate eye protection and protective clothing to prevent skin and eye contact.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Repeated small exposures by any route can cause severe kidney problems. Brain damage may also occur. Skin allergy can develop. May damage the developing fetus.

Exposure limit(s)

TLV: 50 ppm; 127 mg/m3 as CEILING (ACGIH 1993-1994). NIOSH REL: See Appendix D

Poison Class

4

Fire Fighting Measures

Flash Point

111

Autoignition

398

Fire Fighting

Wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Extinguish using dry chemical, foam or carbon dioxide. Water or foam may cause frothing. Water spray may be used to extinguish surrounding fire and cool exposed containers. Water spray will also reduce fume and irritant gases.

Upper exp. limit

15.3

Lower exp. limit

3.2

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Incompatibilities

Chlorosulfonic acid, dimethyl terephthalate, oleum, phosphorus pentasulfide, silvered-copper wire, sodium hydroxide, sulfuric acid, titanium butoxide. Causes ignition at room temperature with chromium trioxide, potassium permanganate, and sodium peroxide. Causes ignition at 100 C with ammonium dichromate, silver chlorate, sodium chloride, and uranyl nitrate.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Carbon dioxide and carbon monoxide may form when heated to decomposition. May produce acrid smoke and irritating fumes when heated to decomposition.

Combustion Products

Toxic gases and vapors may be released if involved in a fire.

Transport Information

HS Code

2905 31 00