Product Identification

Product Name

m-Cresol

Synonyms

2-Oxo-5-methyl-2,3-dihydrofuran
3-Cresol
3-Hydroxytoluene
3-Methylphenol
4-Hydroxy-3-pentenoic acid g-lactone
5-Methyl-2,3-dihydro-2-furanone
5-Methyl-3H-furan-2-one
5-Methylfuran-2(3H)-one
g-Angelica lactone

CAS

108-39-4

CAS

591-12-8

Formula

C5H6O2

Formula

C7H8O

Molecular Weight

108.14

Molecular Weight

98.1

EINECS

203-577-9

EINECS

209-701-8

RTECS

GO6125000

RTECS

LU5075000

RTECS Class

Tumorigen; Mutagen; Reproductive Effector; Primary Irritant

RTECS Class

Other

Merck

12,686

Merck

13,2604

Beilstein/Gmelin

108394

Beilstein/Gmelin

506719

Beilstein Reference

5-17-09-00112

Beilstein Reference

4-06-00-02035

EC Index Number

604-004-00-9

EC Class

Toxic; Corrosive

Physical and Chemical Properties

Appearance

Colorless to yellowish liquid with a phenolic or sweet tarry odor.

Appearance

Light yellow to green liquid.

Solubility in water

Soluble

Solubility in water

10-50 mg/ml

Melting Point

11.5

Melting Point

0

Boiling Point

202.2

Boiling Point

249

Vapor Pressure

0.02 (25 C)

Vapor Pressure

.1

Density

1.0336 g/cm3 (20 C)

Density

1.0904 g/cm3 (12 C)

pKa/pKb

10.09 (pKa)

Partition Coefficient

1.96

Partition Coefficient

.84

Heat Of Vaporization

30.13 kJ/mol

Heat Of Vaporization

68.3

Heat Of Combustion

-3706 kJ/mol

Usage

For making synthetic resins, in disinfectants and fumigants, as industrial solvent, in photographic developers, in explosives.

Saturation Concentration

Approx. 50 ppm (0.005%) at 20 C; 200 ppm (0.02%) at 25 C (calculated)

Vapor Density

3.38

Vapor Density

3.7

Odor threshold

0.037 mg/L in water

Refractive Index

1.4478 (13.2 C)

Refractive Index

1.53651 (13.6 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Inhalation

May cause respiratory tract irritation. Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.

Skin

May cause irritation and dermatitis. May cause cyanosis of the extremities.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

May cause eye irritation. May cause chemical conjunctivitis and corneal damage.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area. Do not store in metal containers.

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Handling

Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Store protected from light. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep from contact with moist air and steam.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Inhalation

Harmful if inhaled. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma. Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Aspiration may lead to pulmonary edema. May cause systemic effects. Inhalation at high concentrations may cause CNS depression and asphixiation.

Skin

Causes skin burns. Prolonged and/or repeated contact may cause irritation and/or dermatitis. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.

Eyes

Causes eye burns. May cause chemical conjunctivitis and corneal damage.

Ingestion

Harmful if swallowed. May cause severe and permanent damage to the digestive tract. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 24/25 34

EC Safety Phrase

S 24/25

EC Safety Phrase

S 36/37/39 45

UN (DOT)

2076

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear neoprene gloves, apron, and/or clothing. Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Prolonged or repeated skin contact may cause dermatitis. May cause liver and kidney damage. May cause fetal effects. Repeated exposure may cause central nervous system damage. Effects may be delayed.

Exposure limit(s)

OSHA PEL: TWA 5 ppm (22 mg/m3) skin NIOSH REL: TWA 2.3 ppm (10 mg/m3) NIOSH IDLH: 250 ppm

Poison Class

3

Fire Fighting Measures

Flash Point

68

Flash Point

86

Autoignition

626

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible solid. Combustible Liquid. Contact with metals may evolve flammable hydrogen gas. Extinguishing media: Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.

Upper exp. limit

7.6

Lower exp. limit

1.1

Fire Potential

Slightly flammable. Combustion requires preheating. Moderate hazard.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water inside containers.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Moisture, strong oxidizing agents.

Incompatibilities

Oxidizing agents

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Emits highly toxic fumes.

Transport Information

UN Number

2076

Hazard Class

6.1

Packing Group

II

HS Code

2907 12 00