Product Identification

Product Name

Dimethyl sulfoxide

Synonyms

Dipirartril-tropico
DMSO
Dolicur
Methanesulfinylmethane
Methyl sulfoxide
N-[4-(Trifluoromethyl)phenyl]acetamide
p-Trifluoromethylacetanilide
Sulfinylbismethane

CAS

67-68-5

CAS

349-97-3

Formula

C2H6OS

Formula

C9H8F3NO

Molecular Weight

78.13

Molecular Weight

203.16

EINECS

206-495-1

EINECS

200-664-3

RTECS

PV6210000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant

Merck

13,3285

Beilstein/Gmelin

2106965

Beilstein/Gmelin

506008

Beilstein Reference

3-12-00-02151

Beilstein Reference

4-01-00-01277

Physical and Chemical Properties

Appearance

Clear, colorless liquid, odorless or with a light sulfur, garlic or oyster-like odor depending on purity.

Solubility in water

Miscible

Melting Point

18.5

Melting Point

208 - 211

Boiling Point

189

Vapor Pressure

0.42 (20 C)

Density

1.101 g/cm3 (20 C)

pKa/pKb

35(at 25℃) (pKa)

Partition Coefficient

-2.03

Heat Of Vaporization

40.8 kJ/mol

Heat Of Combustion

-1715 kJ/mol

Usage

Medication.

Saturation Concentration

592 ppm (0.059%) at 20 C; 790 ppm (0.079%) (calculated)

Vapor Density

2.7

Refractive Index

1.4783 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Ingestion

Seek medical assistance.

Inhalation

TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Remove and isolate contaminated clothing and shoes. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin.

Skin

Contact with molten substance may cause severe burns to skin and eyes. See Inhalation.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Immediately flush with running water for at least 20 minutes.

Eyes

See Inhalation.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.

Hazards Identification

Ingestion

See Inhalation.

Inhalation

May cause respiratory tract irritation. Can produce delayed pulmonary edema.

Skin

May cause irritation with burning pain, itching and redness. Substance is rapidly absorbed through the skin.

Eyes

Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. May cause chemical conjunctivitis.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause garlic smell on the breath and body.

Hazards

Contact with metals may evolve flammable hydrogen gas.

Hazards

Poisonous gases may be produced in fire.

EC Risk Phrase

R 22

EC Risk Phrase

R 36/38

EC Safety Phrase

S 22 36/37

EC Safety Phrase

S 26 36

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Prolonged or repeated skin contact may cause dermatitis. May cause liver and kidney damage. Effects may be delayed.

Exposure limit(s)

OEL-RUSSIA:STEL 20 mg/m3

Poison Class

-

Fire Fighting Measures

Flash Point

95

Autoignition

300

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. Extinguishing media: Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Fighting

Extinguish using agent most appropriate for surrounding fire.

Upper exp. limit

63.0

Lower exp. limit

1.8

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Fire Potential

Slightly flammable. Requires preheating.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Do not flush into a sewer. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.

Small spills/leaks

ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Stability and Reactivity

Disposal Code

1

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong oxidizing agents, strong acids, strong bases.

Decomposition

Carbon monoxide, oxides of sulfur, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Combustion Products

Sulfur dioxide, formaldehyde, and methyl mercaptan can form

Transport Information

UN Number

2811

HS Code

2930 90 70