Product Identification

Product Name

4-Chlorobenzenamine

Synonyms

4-Chloroaniline
p-Chloroaminobenzene
p-Chloroaniline

CAS

106-47-8

Formula

C6H6ClN

Molecular Weight

127.57

EINECS

203-401-0

RTECS

BX0700000

RTECS Class

Tumorigen; Mutagen; Primary Irritant

Merck

13,2136

Beilstein/Gmelin

471350

Beilstein Reference

4-12-00-01166

EC Index Number

612-137-00-9

EC Class

Carcinogenic Category 2; Toxic; Sensitising; Dangerous for the Environment

Physical and Chemical Properties

Appearance

White to pale yellow to tan colored, crystalline solid, slightly sweetish, characteristic amine odor.

Solubility in water

Slightly soluble

Melting Point

69 - 71

Boiling Point

232

Vapor Pressure

0.061 (25 C)

Density

1.43 g/cm3 (20 C)

pKa/pKb

10.03 (pKb)

Partition Coefficient

1.83

Heat Of Vaporization

79.0 kJ/mol

Heat Of Combustion

-7669 kJ/mol

Usage

Dye int, pharmaceuticals, agricultural chemicals.

Vapor Density

4.41

Saturation Concentration

20 ppm (0.002%) at 20 C (calculated)

Refractive Index

1.5546 (87 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Wash hands before eating. Use only in a well ventilated area. Minimize dust generation and accumulation. Do not get on skin or in eyes. Do not ingest or inhale. Wash clothing before reuse.

Hazards Identification

Inhalation

May cause irritation of the respiratory tract with burning pain in the nose and throat, coughing, wheezing, shortness of breath and pulmonary edema. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.

Skin

Causes skin irritation. Harmful if absorbed through the skin. Prolonged and/or repeated contact may cause irritation and/or dermatitis.

Eyes

Causes severe eye irritation.

Ingestion

Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. Overexposure may cause methemoglobinemia.

Hazards

Containers may explode when heated.

EC Risk Phrase

R 45 23/24/25 43 50/53

EC Safety Phrase

S 53 45 60 61

UN (DOT)

2018

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause liver and kidney damage. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. May cause cancer according to animal studies. May cause reproductive and fetal effects.

Fire Fighting Measures

Flash Point

90

Autoignition

> 500

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Upper exp. limit

8.8

Lower exp. limit

2.2

Fire Potential

Very flammable.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Reduce airborne dust and prevent scattering by moistening with water. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Acids, acid chlorides, acid anhydrides, chloroformates, and strong oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Irritating and toxic hydrogen chloride and oxides of nitrogen may form in fires.

Transport Information

UN Number

2018

Hazard Class

6.1

Packing Group

II

HS Code

2921 42 10