2-Hydroxy-1-ethanethiol(60-24-2)
Product Identification
Product Name
2-Hydroxy-1-ethanethiol
Synonyms
2-Hydroxy-1-ethanethiol
2-Mercaptoethanol
2-Sulfanylethanol
Monothioethyleneglycol
CAS
60-24-2
Formula
C2H6OS
Molecular Weight
78.13
EINECS
200-464-6
RTECS
KL5600000
RTECS Class
Mutagen; Primary Irritant
Merck
13,5894
Beilstein/Gmelin
773648
Beilstein Reference
4-01-00-02428
EC Class
toxic, corrosive, dangerous for the environment
Physical and Chemical Properties
Appearance
Colorless liquid with a faint characteristic odor.
Solubility in water
Soluble
Melting Point
-100
Boiling Point
157
Vapor Pressure
1.0 (25 C)
Density
1.1317 g/cm3 (0 C)
pKa/pKb
9.74 (pKa)
Partition Coefficient
-.326
Heat Of Vaporization
45.9 kJ/mol
Usage
Solvent for dyestuffs, intermediate for producing dyestuffs, pharmaceuticals, rubber chemicals, flotation agents, insecticides, plasticizers, water-soluble reducing agent, biochemical reagent, pvc stabilizers, agricultural chemicals, textile auxiliary.
Saturation Concentration
81600 ppm (8.2%) at 20 C
Vapor Density
2.7
Odor threshold
0.38 mg/m3
Refractive Index
1.4963 (20 C)
First Aid Measures
Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Hazards Identification
Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause dyspnea (difficult breathing from shortness of breath). Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis, cold extremities and rapid pulse. Mercaptans may cause nausea and headache.
Skin
May be fatal if absorbed through the skin. Causes irritation with burning pain, itching, and redness.
Eyes
May cause severe eye irritation. May result in corneal injury.
Ingestion
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause muscle paralysis, respiratory failure, and possible death.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
EC Risk Phrase
R 20/22 24 34 51/53
EC Safety Phrase
S 26 36/37/39 45 61
UN (DOT)
2966
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Prolonged or repeated skin contact may cause defatting and dermatitis. Repeated or prolonged exposure may cause CNS stimulation.
Exposure limit(s)
OEL-RUSSIA:STEL 1 mg/m3
Poison Class
3
Fire Fighting Measures
Flash Point
68
Autoignition
295
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible Liquid. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Upper exp. limit
18
Lower exp. limit
2.3
Fire Potential
May burn but does not ignite readily.
Accidental Release Measures
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation.
Stability and Reactivity
Disposal Code
6
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizers, calcium hypochlorite, metals, strong acids, caustics, aliphatic amines, isocyanates.
Decomposition
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.