Product Identification

Product Name

5-Amino-2-chloronitrobenzene

Synonyms

4-Chloro-3-nitrobenzenamine

CAS

635-22-3

Formula

C6H5ClN2O2

Molecular Weight

172.57

EINECS

211-231-3

RTECS

BX1750000

RTECS Class

Reproductive Effector; Primary Irritant

Beilstein/Gmelin

1309394

Beilstein Reference

4-12-00-01674

EC Index Number

610-006-00-0

EC Class

very toxic, dangerous for the environment

Physical and Chemical Properties

Appearance

Yellow to tan powder.

Solubility in water

Insoluble

Melting Point

102 - 103

Partition Coefficient

2.09

Usage

Intermediate in the manufacture of azo dyes, pharmaceuticals and other organic compounds.

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.

Skin

May cause skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

May cause eye irritation. The toxicological properties of this material have not been fully investigated.

Ingestion

Harmful if swallowed. May cause irritation of the digestive tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May form methemoglobin which in sufficient concentration causes cyanosis.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 26/27/28 33 51/53

EC Safety Phrase

S 28 36/37 45 61

UN (DOT)

2237

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

CNS effects include headache, dizziness, altered mental status, confusion (lethargy progressing coma), seizures, syncope; occur secondary to CNS hypoxia, usually with levels > 20%.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong bases.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2237

Hazard Class

6.1

Packing Group

III

HS Code

2921 42 10