Product Identification

Product Name

2-Aminophenol

Synonyms

2,2,2-Trifluoro-1-phenylethanol
2,2,2-Trifluorophenylethanol
2-Hydroxyaniline
Benzenemethanol, alpha-(trifluoromethyl)-, (+/-)-
o-Aminophenol

CAS

340-05-6

CAS

95-55-6

Formula

C6H7NO

Formula

C8H7F3O

Molecular Weight

176.13

Molecular Weight

109.13

EINECS

202-431-1

EINECS

206-429-1

RTECS

SJ4950000

RTECS Class

Drug; Mutagen; Reproductive Effector; Primary Irritant

Merck

13,460

Beilstein/Gmelin

3197623

Beilstein/Gmelin

606075

Beilstein Reference

4-06-00-03044

Beilstein Reference

4-13-00-00805

EC Index Number

612-033-00-3

EC Class

Harmful; Mutagenic Category 3

Physical and Chemical Properties

Appearance

Colorless liquid.

Appearance

Off-white crystals or beige powder.

Solubility in water

20 g/L (20 C)

Boiling Point

235

Boiling Point

64 - 65 (5 torr)

Vapor Pressure

0.035 (25 C)

Density

1.293 g/cm3 (20 C)

Density

1.328 g/cm3

pKa/pKb

9.76 (pKa)

Partition Coefficient

.62

Heat Of Vaporization

49.0 kJ/mol

Heat Of Combustion

-3171 kJ/mol

Usage

Manufacture azo and sulfur dyes.

Vapor Density

6.07

Refractive Index

1.46 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Inhalation

Causes irritation of mucous membrane. Inhalation of vapors causes irritation of the mucous membranes.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Causes skin irritation.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Causes eye irritation.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Ingestion

May cause irritation of the digestive tract.

Inhalation

Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation.

Skin

Causes skin irritation. May cause dermatitis.

Eyes

Causes eye irritation.

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Exposure may cause anemia and other blood abnormalities. May be harmful if swallowed.

Hazards

Containers may explode when heated.

EC Risk Phrase

R 20/22 68

EC Risk Phrase

R 36/38

EC Safety Phrase

S 26 36

EC Safety Phrase

S 28 36/37

UN (DOT)

2512

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Prolonged or repeated inhalation of dusts may cause neurological damage. May cause liver and kidney damage. May cause reproductive and fetal effects.

Poison Class

3

Fire Fighting Measures

Flash Point

84

Flash Point

96

Autoignition

190

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Combustible Liquid. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition. Use a spark-proof tool.

Small spills/leaks

Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Stability

No data.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, acids, acid anhydrides, acid chlorides,chloroformates.

Incompatibilities

Strong oxidizing agents, reducing agents, acid anhydrides, acid chlorides.

Disposal Code

3

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2512

Hazard Class

6.1

Packing Group

III

HS Code

2922 29 00