Product Identification

Product Name

(R)-Laenitrile

Synonyms

(R)-alpha-((6-o-beta-D-Glucopyranosyl-beta-D-glucopyranosyl)oxy)benzeneacetonitrile
Amygdalin
Amygdaloside
Mandelonitrile beta-gentiobioside
R-Amygdalin
Vitamin B-17

CAS

29883-15-6

Formula

C20H27NO11

Molecular Weight

457.43

EINECS

249-925-3

RTECS

OO8450000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data

Merck

13,701

Beilstein/Gmelin

66856

Beilstein Reference

5-17-08-00118

Physical and Chemical Properties

Appearance

Odorless, white powder.

Solubility in water

83 g/L

Melting Point

226

Usage

Studied extensively as a potential anti-cancer drug. Sold as a dietary supplement although no anti-cancer activity has been identified.

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed.

EC Risk Phrase

R 22

EC Safety Phrase

S 22 36/37

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Headaches, dizziness, lightheadedness, disorientation, irritability, unresponsiveness, lethargy, stupor, weakness, paralysis, areflexia, syncope coma, and seizures may follow gastrointestinal symptoms. Chronic consumption of plants containing high concentrations of cyanogenic glycosides has been associated with polyneuropathy which include optic atrophy, nerve deafness, spastic paraparesis, ataxia, clonus and peripheral neuropathy.

Fire Fighting Measures

Fire Fighting

Containers can build up pressure if exposed to heat and/or fire. In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents, strong acids, strong bases.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.