Product Identification

Product Name

3-((Methoxycarbonyl)amino)phenyl (3-methylphenyl)carbamate

Synonyms

3-(Carbomethoxyamino)phenyl 3-methylcarbanilate
3-Methoxycarbonylaminophenyl-N-3'-methylphenylcarbamate
EP-452
Fenmedifam
Kemifam
Methyl-3-hydroxycarbanilate-3-methylcarbanilate

CAS

13684-63-4

Formula

C16H16N2O4

Molecular Weight

300.31

EINECS

237-199-0

RTECS

FD9050000

RTECS Class

Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector

Merck

12,7384

Beilstein/Gmelin

2395027

Physical and Chemical Properties

Appearance

Colorless crystals or white powder.

Solubility in water

4.7 mg/L

Melting Point

139-142

Boiling Point

181 (13 torr)

Vapor Pressure

1E-11 (25 C)

Density

0.34-0.54 g/cm3 (20 C)

Usage

Post emergent herbicide for control of certain broadleaf & grass weeds, recommended for use in sugar beets, strawberries & sunflowers.

First Aid Measures

Ingestion

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.

Inhalation

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.

Skin

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Respiratory failure, requiring ventilatory support, has been reported following ingestions.

Skin

Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.

Ingestion

Nausea, vomiting and diarrhea may occur.

Exposure Controls/Personal Protection

Personal Protection

Wear goggles to prevent splashing into eyes.

Respirators

Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.

Exposure Effects

Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.

Poison Class

5

Fire Fighting Measures

Fire Fighting

Fires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

Accidental Release Measures

Small spills/leaks

If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity

Incompatibilities

Incompatible with strong acids and bases, and especially

Stability

Very low volatility; no changes were observed when held for 6 days at 50 C; hydrolysis at 22 C in buffer solution, 50% loss occurred in 70 days at pH 5, 24 hr at pH 7, 10 min at pH 9. Shelf life over 1 yr.