Product Identification

Product Name

Flurandrenolide

Synonyms

6a-Fluoro-11b,16a,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide
Cordran
Drenison
Fluorandrenolone
Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-

CAS

1524-88-5

Formula

C24H33FO6

Molecular Weight

436.52

EINECS

216-196-8

RTECS

TU5024800

RTECS Class

Drug; Mutagen; Hormone

Merck

12,4232

Beilstein/Gmelin

1442935

Beilstein Reference

5-19-06-00547

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

209 - 219

Boiling Point

579

Vapor Pressure

8E-16 (25 C)

pKa/pKb

12.84 (pKa)

Heat Of Vaporization

99.5 kJ/mol

Usage

Used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Handling and Storage

Storage

Keep tightly closed. Store in a cool dry place.

Hazards Identification

Inhalation

Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. Readily absorbed through skin.

Eyes

May cause eye irritation.

Hazards

Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Exposure Effects

Properties of this material have not yet been prepared. Any recommendations are of a general nature. Many chemicals cause irritation of the eyes, skin, and respiratory tract. In severe cases respiratory tract irritation can progress to ARDS/acute lung injury which may be delayed in onset for up to 24 to 72 hours in some cases Irritation or burns of the esophagus or gastrointestinal tract are also possible if caustic or irritant chemicals are ingested. ALWAYS contact your local poision control authority or medical professional for assistance.

Fire Fighting Measures

Flash Point

304

Fire Fighting

Extinguish using Noncombustible. Use extinguishing media appropriate to surrounding fire conditions. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Hydrogen fluoride.