Product Identification

Product Name

Ethane-1,2-diylbis(oxyethane-2,1-diyl) bis(2-methylacrylate)

Synonyms

1,2-bis(2-(methacryloyloxy)ethoxy)ethane
2,2'-Ethylenedioxydiethyl dimethacrylate
Ethylenebis(oxyethylene) methacrylate
NK ester 3G
Tedma
TGM 3

CAS

109-16-0

Formula

C14H22O6

Molecular Weight

286.36

EINECS

203-652-6

RTECS

OZ4100000

RTECS Class

Mutagen

Beilstein/Gmelin

1797351

Beilstein Reference

4-02-00-01531

Physical and Chemical Properties

Boiling Point

135 - 139 (1 torr)

Density

1.0741 g/cm3 (20 C)

Partition Coefficient

1.88

Usage

Crosslinking agent for hard contact lenses.

Refractive Index

1.4623 (20 C)

First Aid Measures

Ingestion

Significant systemic toxicity is not expected after acute ingestion; gastrointestinal decontamination is generally not warranted.

Inhalation

If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Respiratory depression, pulmonary edema, emphysema, and atelectasis have occurred in animals following large doses.

Skin

Allergic contact dermatitis has been reported. Eczematous reactions of onychial and paronychial tissues have been reported in patients using acrylic plastic nails. Dystrophic nail changes may persist for months. Irreversible loss of the fingernails has occurred.

Ingestion

Anorexia and nausea has been reported from inhalational exposure. Stomatitis has resulted from contact. Administration to rats by lavage failed to produce gastric lesions.

Exposure Controls/Personal Protection

Personal Protection

Suitable protective clothing and self-contained resp protective apparatus should be available for use by those who may have to rescue persons overcome by fumes.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Exposure Effects

Paresthesia have been reported. Headache, irritability, drowsiness and dizziness may occur. There is no evidence of methyl methacrylate-induced teratogenicity in humans but there are conflicting reports in animals.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.