Product Identification

Product Name

L-Leu

Synonyms

(2S)-2-Amino-4-methylpentanoic acid
(S)-2-Amino-4-methylvaleric acid
2-Amino-4-methylpentanoic acid
L-a-Aminoisocaproic acid
L-Norvaline, 4-methyl-
Pentanoic acid, 2-amino-4-methyl-, (S)-

CAS

61-90-5

Formula

C6H13NO2

Molecular Weight

131.18

EINECS

200-522-0

RTECS

OH2850000

RTECS Class

Mutagen; Reproductive Effector

Merck

13,5470

Beilstein/Gmelin

1721722

Beilstein Reference

4-04-00-02738

Physical and Chemical Properties

Appearance

White solid. Practically odorless

Solubility in water

Very soluble

Melting Point

300

Boiling Point

sublimes

Density

1.165 g/cm3

pKa/pKb

2.55 (pKa)

Partition Coefficient

-1.68

Usage

Nutrient.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. Get medical aid if cough or other symptoms appear.

Skin

Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation.

Eyes

May cause eye irritation. No information regarding eye irritation and other potential effects was found.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective gloves to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Substance is noncombustible; use agent most appropriate to extinguish surrounding fire.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.

Stability and Reactivity

Disposal Code

31

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Transport Information

HS Code

2922 49 95