Product Identification

Product Name

2,6-Dimethyl-4-heptanone

Synonyms

2,6-Dimethyl-4-heptanone
2,6-Dimethylheptan-4-one
Isovalerone
Valerone

CAS

108-83-8

Formula

C9H18O

Molecular Weight

142.24

EINECS

203-620-1

RTECS

MJ5775000

RTECS Class

Human Data; Primary Irritant

Beilstein/Gmelin

1743163

Beilstein Reference

4-01-00-03360

EC Index Number

606-005-00-X

EC Class

Flammable; Irritant

Physical and Chemical Properties

Appearance

Colorless liquid with a mild peppermint odor.

Solubility in water

500 mg/L

Melting Point

-46

Boiling Point

165

Vapor Pressure

1.7 (20 C)

Density

0.806 g/cm3 (20 C)

Heat Of Vaporization

37.0 kJ/mol

Heat Of Combustion

-5300 kJ/mol

Usage

Solvent for nitrocellulose, for milled crepe rubber, vinylite, synthetic coatings and as a dispersant for organosol type resins, intermediate in synthesis of inhibitors, pharmaceuticals, dyes, & insecticides.

Saturation Concentration

9.3 g/m3 at 20 C

Vapor Density

4.9

Odor threshold

< 0.11 ppm

Refractive Index

1.4101 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Inhalation of vapors irritates the respiratory tract. May cause coughing, dizziness, dullness, nausea, vomiting and headache. Higher concentrations can produce central nervous system depression, narcosis, and unconsciousness. The odor of this material is recognized at levels well below those which cause adverse effects and should be sufficient warning against overexposure.

Skin

May cause irritation with redness and pain.

Eyes

Liquid and vapor causes irritation, redness, and pain.

Ingestion

Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.

Hazards

Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

EC Risk Phrase

R 10 37

EC Safety Phrase

S 24

UN (DOT)

1157

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Chronic exposure may cause skin effects. May cause liver and kidney effects based upon studies with laboratory animals.

Exposure limit(s)

TLV: 25 ppm; 145 mg/m3 (as TWA) (ACGIH 1997). OSHA PEL: TWA 50 ppm (290 mg/m3) NIOSH REL: TWA 25 ppm (150 mg/m3) NIOSH IDLH: 500 ppm

Poison Class

4

Fire Fighting Measures

Flash Point

49

Autoignition

396

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: Use water spray to cool fire-exposed containers. Water may be ineffective. In case of fire, use water fog, dry chemical, carbon dioxide, or regular foam. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water.

Upper exp. limit

7.1

Lower exp. limit

.8

Fire Potential

HIGHLY FLAMMABLE.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity

Disposal Code

1

Stability

Stable under normal temperatures and pressures. However, forms peroxides of unknown stability.

Incompatibilities

Strong oxidizers. May attack some forms of plastic, rubber and coatings.

Decomposition

Carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1157

Hazard Class

3

Packing Group

III

HS Code

2914 19 90