Anthranilic acid(118-92-3)
Product Identification
Product Name
Anthranilic acid
Synonyms
1-Amino-2-carboxybenzene
2-Aminobenzoic acid
2-Carboxyaniline
Benzoic acid, o-Amino
Methanone, (2-aminophenyl)(4-methylphenyl)-
o-Aminobenzoic acid
CAS
118-92-3
CAS
36192-63-9
Formula
C14H13NO
Formula
C7H7NO2
Molecular Weight
137.13999999999999
Molecular Weight
211.26
EINECS
252-905-7
EINECS
204-287-5
RTECS
CB2450000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector
Merck
13,421
Beilstein/Gmelin
2210628
Beilstein/Gmelin
471803
Beilstein Reference
4-14-00-01004
Beilstein Reference
3-14-00-00248
EC Class
irritant
Physical and Chemical Properties
Appearance
Odorless white to pale-yellow or tan crystalline powder with a sweetish taste.
Appearance
Yellow crystalline powder crystalline powder.
Solubility in water
Very soluble
Melting Point
95
Melting Point
144
Boiling Point
312
Vapor Pressure
0.008 (53 C)
Density
1.362 g/cm3
pKa/pKb
4.95 (pKa)
Partition Coefficient
1.21
Heat Of Vaporization
58.4 kJ/mol
Usage
Chemical intermediate for ci acid yellow 121, vat violet 13, vat blue 1, ci direct brown 112, mordant yellow, mordant red 9, mordant brown 40, & pigment red 60, & for its esters used in perfumes & fungicides, & in saccharin, cadmium salt- an ascaricide in swine, mold inhibitor in soya sauce.
Vapor Density
4.7
Refractive Index
1.578 (144 C)
First Aid Measures
Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.
Skin
Causes skin irritation.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Causes eye irritation. May cause chemical conjunctivitis.
Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and Storage
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards Identification
Inhalation
Causes respiratory tract irritation. May cause effects similar to those described for ingestion. Can produce delayed pulmonary edema.
Skin
Causes skin irritation.
Eyes
Causes eye irritation. May cause chemical conjunctivitis.
Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause acidosis, itching, rash, fever, methemoglobinemia, and possibly hepatitis.
EC Risk Phrase
R 36/37
EC Safety Phrase
S 26 36
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Exposure Effects
Effects may be delayed.
Poison Class
4
Fire Fighting Measures
Flash Point
150
Autoignition
> 530
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Potential
This chemical is combustible.
Accidental Release Measures
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability and Reactivity
Disposal Code
4
Incompatibilities
Acid anhydrides, acid chlorides, acids, chloroformates, strong oxidizing agents, strong reducing agents.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions. Decomposes on exposure to light.
Incompatibilities
Strong oxidizing agents, direct light.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.