Product Identification

Product Name

3-Aminobenzotrifluoride

Synonyms

3-(Trifluoromethyl)aniline
3-Aminobenzotrifluoride
alpha,alpha,alpha-trifluoro-m-toluidine

CAS

98-16-8

Formula

C7H6F3N

Molecular Weight

161.13

EINECS

202-643-4

RTECS

XU9180000

RTECS Class

Primary Irritant

Beilstein/Gmelin

387672

Beilstein Reference

4-12-00-01843

EC Class

toxic, irritant

Physical and Chemical Properties

Appearance

A colorless liquid with a fishlike odor.

Solubility in water

Slightly soluble

Melting Point

5 - 7

Boiling Point

187

Vapor Pressure

0.64 (25 C)

Density

1.30467 g/cm3 (13 C)

pKa/pKb

10.63 (pKb)

Partition Coefficient

2.39

Heat Of Vaporization

42.3 kJ/mol

Heat Of Combustion

-4366 kJ/mol

Usage

Intermediate in manufacture of phenothiazine deriv.

Vapor Density

5.56

Refractive Index

1.4847 (12.5 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Aspiration may lead to pulmonary edema. Can produce delayed pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.

Skin

Causes skin irritation. May cause cyanosis of the extremities.

Eyes

Causes eye irritation. May cause chemical conjunctivitis and corneal damage.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Hazards

Cylinder may explode in heat of fire. When heated to decomposition, it emits very toxic fumes of fluorides and nitrogen oxides.

EC Risk Phrase

R 21/22 26 33 36/38

EC Safety Phrase

S 26 28 36/37/39 45

UN (DOT)

2948

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Flash Point

85

Autoignition

>600

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

This material may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2948

Hazard Class

6.1

Packing Group

II

HS Code

2921 43 00