Product Identification

Product Name

3-Amino-1-Propanol

Synonyms

3-Aminopropan-1-ol
3-Aminopropanol
3-Hydroxy-1-aminopropane
3-Hydroxy-1-propylamine
beta-Alaninol
gamma-Aminopropanol

CAS

156-87-6

Formula

C3H9NO

Molecular Weight

75.11

EINECS

205-864-4

RTECS

UA5600000

RTECS Class

Reproductive Effector; Primary Irritant

Beilstein/Gmelin

4231142

EC Class

harmful, corrosive

Physical and Chemical Properties

Appearance

Clear colorless to pale yellow liquid with a fishy odor.

Solubility in water

Miscible

Melting Point

11

Boiling Point

187

Vapor Pressure

0.18 (25 C)

Density

0.982 g/cm3 (20 C)

pKa/pKb

4.09 (pKa)

Partition Coefficient

-1.12

Heat Of Vaporization

49.5 kJ/mol

Usage

Chemical intermediate for dexpanthenol, a gastrointestinal drug.

Vapor Density

2.59

Refractive Index

1.46 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Eyes

Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes chemical burns to the respiratory tract. Aspiration may lead to pulmonary edema. May cause systemic effects. Inhalation at high concentrations may cause CNS depression and asphixiation.

Skin

Causes skin burns. May be harmful if absorbed through the skin. May cause irritation and dermatitis. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.

Eyes

Causes eye burns. May cause chemical conjunctivitis and corneal damage.

Ingestion

May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 21 34

EC Safety Phrase

S 23 26 36

UN (DOT)

2735

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Effects may be delayed.

Poison Class

4

Fire Fighting Measures

Flash Point

79

Autoignition

375

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Combustible Liquid. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers.

Upper exp. limit

10.6

Lower exp. limit

2.5

Fire Potential

Combustible liquid and vapor.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity

Disposal Code

1

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Combustion Products

Toxic oxides of nitrogen may form in fire.

Transport Information

UN Number

2735

Hazard Class

8

Packing Group

I; II; III

HS Code

2922 19 80