Product Identification

Product Name

Hyoscine N-butyl bromide

Synonyms

3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1a,2b,4b,5a,7b)-
Hyoscine-N-butyl bromide
N-Butylscopolammonium bromide
Scopolamine bromobutylate

CAS

149-64-4

Formula

C21H30BrNO4

Molecular Weight

440.38

EINECS

205-744-1

RTECS

YM3500000

RTECS Class

Drug

Merck

12,1624

Beilstein/Gmelin

4117801

Beilstein Reference

6-27

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

50 g/L

Melting Point

139 - 141

Usage

Competitive muscarinic acetylcholine receptor antagonist and antispasmodic.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

Toxic if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. Toxic if absorbed through skin.

Eyes

May cause eye irritation.

Ingestion

Toxic if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

23/24/25

EC Safety Phrase

36/37/39 45

UN (DOT)

1544

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Toxic. Toxic by inhalation, in contact with skin and if swallowed. Target organ(s): Nerves.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Potential

Non-Combustible

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1544

Hazard Class

6.1

Packing Group

III