Product Identification

Product Name

Xylocaine

Synonyms

2-(Diethylamino)-2',6'-acetoxylidide
alpha-diethylamino-2,6-dimethylacetanilide
alpha-Diethylaminoaceto-2,6-xylidide
Anestacon
Diethylaminoacet-2,6-xylidide
Diethylaminoaceto-2,6-xylidide

CAS

137-58-6

Formula

C14H22N2O

Molecular Weight

234.34

EINECS

205-302-8

RTECS

AN7525000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data

Merck

12,5505

Beilstein/Gmelin

2215784

Beilstein Reference

4-12-00-02538

Physical and Chemical Properties

Appearance

White to yellow powder with a characteristic odor.

Solubility in water

Slightly soluble

Melting Point

70

Boiling Point

351

Vapor Pressure

4E-5 (25 C)

Density

1.04 g/cm3

pKa/pKb

5.47 (pKb)

Partition Coefficient

2.36

Heat Of Vaporization

59.7 kJ/mol

Usage

Medication.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. May cause adverse central nervous system effects including headache, convulsions, and possible death.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system effects. May cause headache, nausea, fatigue, and dizziness.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Generalized depression of vital signs may follow a period of transient physiological stimulation. CNS effects invariably precede significant cardiovascular toxicity, except following massive iv injection.

Fire Fighting Measures

Flash Point

166

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidants.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.