Product Identification

Product Name

N-Ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylmethyl)propanamide

Synonyms

Bistropamide
Epitromina
Mydriacyl
Mydriat
N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamine
N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide

CAS

1508-75-4

Formula

C17H20N2O2

Molecular Weight

284.36

EINECS

216-140-2

RTECS

CY1487860

RTECS Class

Drug

Merck

12,9911

Beilstein/Gmelin

285563

Beilstein Reference

5-22-09-00359

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

Insoluble

Boiling Point

493

Vapor Pressure

2E-10 (25 C)

pKa/pKb

8.51 (pKb)

Heat Of Vaporization

80.0 kJ/mol

Usage

Acetylcholine receptor antagonist.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C

Hazards Identification

Inhalation

Harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.

Skin

Causes skin irritation. Harmful if absorbed through skin.

Eyes

Causes eye irritation.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/21/22 36/37/38 42/43

EC Safety Phrase

22 26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Harmful. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. May cause sensitization by inhalation and skin contact. Target organ(s): Nerves.

Fire Fighting Measures

Flash Point

252

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.