Product Identification

Product Name

4-Methylthiophenol

Synonyms

1-Mercapto-4-methylbenzene
4-Mercaptotoluene
Benzenethiol, 4-methyl-
p-Toluenethiol
-Tolyl mercaptan

CAS

106-45-6

Formula

C7H8S

Molecular Weight

124.21

EINECS

203-399-1

RTECS

XT8925000

RTECS Class

Other

Merck

12,9461

Beilstein/Gmelin

605761

Beilstein Reference

4-06-00-02153

EC Class

Irritant

Physical and Chemical Properties

Appearance

White, solid, leaflets, also cream to white, moist crystals, musty odor.

Solubility in water

36 mg/L (25 C)

Melting Point

39 - 42

Boiling Point

195

Vapor Pressure

0.6 (25 C)

Density

1.0220 g/cm3 (51C)

pKa/pKb

6.82 (pKa)

Partition Coefficient

2.98

Heat Of Vaporization

41.4 kJ/mol

Usage

Antiseptic, dermatologic unspecified isomer.

Odor threshold

1.0X10-4 mg/L

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

Causes skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

Causes eye irritation. The toxicological properties of this material have not been fully investigated.

Ingestion

The toxicological properties of this substance have not been fully investigated. Causes gastrointestinal tract irritation.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 20/21/22 36/38

EC Safety Phrase

S 28 36/37 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Abnormally low blood pressure, reduced body temperature, rapid breathing, and rapid heart rate may develop with severe toxicity. Initial CNS excitation, including seizures, is commonly followed by CNS depression ranging from lethargy to coma and death. Fetotoxicity and skeletal abnormalities have been reported in animal experiments.

Fire Fighting Measures

Flash Point

68

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode when heated. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use agent most appropriate to extinguish fire.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Oxidizing agents

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, oxides of sulfur, carbon dioxide, hydrogen sulfide.

Combustion Products

When heated to decomp, it emits toxic fumes of sulfur oxides.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2930 90 70