Product Identification

Product Name

17-Hydroxy-7alpha-methyl-19-norpregn-5(10)-en-20-yn-3-one

Synonyms

(7a,17a)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-7-methyl-, (7alpha,17alpha)-
7a-Methyl-17a-ethynyl-17b-hydroxy-5(10)-estren-3-one
7a-Methyl-D5,10-norethindrone

CAS

5630-53-5

Formula

C21H28O2

Molecular Weight

312.45

EINECS

227-069-1

Merck

12,9566

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

167

Boiling Point

447

Vapor Pressure

7.0E-10 (25 C)

Density

1.13 g/cm3 (20 C)

pKa/pKb

13.10 (pKa)

Partition Coefficient

4.03

Heat Of Vaporization

81.4 kJ/mol

Usage

Used mainly for hormone replacement therapy in post-menopausal women.

Handling and Storage

Storage

Store in original container in a cool dark place.

Hazards Identification

Inhalation

Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.

Skin

Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.

Eyes

Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.

Ingestion

If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.

Exposure Controls/Personal Protection

Personal Protection

Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.

Fire Fighting Measures

Flash Point

191

Fire Fighting

Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.

Stability and Reactivity

Combustion Products

Emits toxic fumes under fire conditions.