Product Identification

Product Name

11b,17a-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione

Synonyms

11b,17a-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
21-Desoxy-9a-fluoro-6-methylprednisolone
6a-Methyl-9a-fluoro-21-desoxyprednisolone
9a-Fluoro-11b,17a-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
Delmeson
Oxylone

CAS

426-13-1

Formula

C22H29FO4

Molecular Weight

376.47

EINECS

207-041-5

RTECS

TU3834100

RTECS Class

Drug

Merck

12,4213

Beilstein/Gmelin

3172388

Beilstein Reference

4-08-00-03006

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

292 - 303

Vapor Pressure

3E-13 (25 C)

pKa/pKb

12.42 (pKa)

Heat Of Vaporization

92/2 kJ/mol

Usage

Medication to control inflammation of eye tissue.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Harmful. Harmful by inhalation, in contact with skin and if swallowed. Target organ(s): Eyes.

Fire Fighting Measures

Flash Point

273

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, Strong acids, Acid chlorides, Acid anhydrides.

Decomposition

Carbon monoxide, Carbon dioxide, Hydrogen fluoride.

Hazards Identification

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/21/22

EC Safety Phrase

36