Product Identification

Product Name

Frambinone

Synonyms

4-(4-Hydroxyphenyl)-2-butanone
4-(4-Hydroxyphenyl)butan-2-one
4-(p-Hydroxyphenyl)-2-butanone
Oxyphenylon
p-Hydroxybenzyl acetone
Raspberry ketone

CAS

5471-51-2

Formula

C10H12O2

Molecular Weight

164.2

EINECS

226-806-4

RTECS

EL8925000

RTECS Class

Other

Beilstein/Gmelin

776080

Beilstein Reference

4-08-00-00506

Physical and Chemical Properties

Appearance

White powder. Raspberry odor.

Solubility in water

Slightly soluble

Melting Point

83 - 84

Boiling Point

292

Vapor Pressure

0.001 (25 C)

pKa/pKb

10.18 (pKa)

Partition Coefficient

.94

Heat Of Vaporization

55.3 kJ/mol

Usage

The primary aroma compound of red raspberries. It is used in perfumery, in cosmetics, and as a food additive to impart a fruity odor.

Vapor Density

5.66

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.

Inhalation

May cause respiratory tract irritation. May cause irritation of the mucous membranes.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

EC Risk Phrase

R 22 36/37/38

EC Safety Phrase

S 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures

Flash Point

123

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.