Product Identification

Product Name

4-(Methylmercapto)aniline

Synonyms

4-(Methylthio)aniline
4-(Methylthio)benzenamine
4-Aminothioanisole
p-Aminophenyl methyl sulfide
p-Thioanisidine
p-Thiomethoxyaniline

CAS

104-96-1

Formula

C7H9NS

Molecular Weight

139.21

EINECS

203-256-3

RTECS

BY6302000

RTECS Class

Other

Beilstein/Gmelin

774506

Beilstein Reference

4-13-00-01289

Physical and Chemical Properties

Appearance

Brown - pale-yellow liquid. With a stench.

Solubility in water

Slightly soluble

Melting Point

156 - 158

Boiling Point

74 (0.1 torr)

Density

1.1379 g/cm3 (20 C)

pKa/pKb

9.64 (pKb)

Vapor Density

4.8

Refractive Index

1.6306 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.

Hazards Identification

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis, cold extremities and rapid pulse. Mercaptans may cause nausea and headache. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. Mercaptans may cause nausea and headache. Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis, cold extremities and rapid pulse.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 20/21/22 36/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

2810

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death.

Fire Fighting Measures

Flash Point

> 110

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2810

Hazard Class

6.1

Packing Group

I; II; III