Product Identification

Product Name

1-Amino-3-chlorobenzene

Synonyms

1-Amino-3-chlorobenzene
3-Chlorobenzamine
m-Chloroaniline
Orange GC base

CAS

108-42-9

Formula

C6H6ClN

Molecular Weight

127.57

EINECS

203-581-0

RTECS

BX0350000

RTECS Class

Tumorigen; Mutagen

Merck

13,2136

Beilstein/Gmelin

605969

Beilstein Reference

4-12-00-01137

EC Index Number

612-010-00-8

EC Class

toxic, dangerous for the environment

Physical and Chemical Properties

Appearance

Colorless to light amber liquid, characteristic sweet odor.

Solubility in water

Insoluble

Melting Point

-10.4

Boiling Point

230.5

Vapor Pressure

8.7 (100 C)

Density

1.216 g/cm3 (20 C)

pKa/pKb

10.48 (pKb)

Partition Coefficient

1.88

Heat Of Vaporization

60.9 kJ/mol

Heat Of Combustion

-770 kJ/mol

Usage

Chemical intermediate for the herbicide chlorpropham, m-chlorophenyl isocyanurate, pharmaceuticals, & azo dyes & pigments.

Saturation Concentration

Less than 130 ppm at 30 C (calculated)

Vapor Density

1.206

Refractive Index

1.5941 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.

Hazards Identification

Inhalation

Harmful if inhaled. May cause respiratory tract irritation. May cause effects similar to those described for ingestion.

Skin

Causes skin burns. Substance is rapidly absorbed through the skin. If absorbed, may cause symptoms similar to those for ingestion.

Eyes

Causes eye burns.

Ingestion

Harmful if swallowed. May cause irritation of the digestive tract. May cause liver and kidney damage. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May cause central nervous system effects. May cause discoloration of the lips, tongue, and mucous membranes.

Hazards

Containers may explode when heated.

EC Risk Phrase

R 23/24/25 33 50/53

EC Safety Phrase

S 28 36/37 45 60 61

UN (DOT)

2019

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause cancer according to animal studies.

Poison Class

3

Fire Fighting Measures

Flash Point

124

Autoignition

705

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam. Do NOT use straight streams of water.

Upper exp. limit

8.8

Lower exp. limit

1.5

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Acids, acid chlorides, acid anhydrides, strong oxidizing agents, chloroformates.

Stability

Stable under normal temperatures and pressures. Substance may undergo color change upon exposure to light and air.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Combustion Products

Irritating and toxic hydrogen chloride and oxides of nitrogen may form in fires.

Transport Information

UN Number

2019

Hazard Class

6.1

Packing Group

II

HS Code

2921 42 10