Product Identification

Product Name

H-Sar-OH

Synonyms

(Methylamino)acetic acid
(Methylamino)ethanoic acid
1-Ethyl-2-pyrrolidinone
1-Ethylpyrrolidin-2-one
2-Methylaminoacetic acid
N-Ethylpyrrolidinone
N-Ethylpyrrolidone
N-Methylaminoacetic acid
N-Methylglycine
Sarcosinic acid

CAS

107-97-1

CAS

2687-91-4

Formula

C3H7NO2

Formula

C6H11NO

Molecular Weight

113.15

Molecular Weight

89.09

EINECS

203-538-6

EINECS

220-250-6

RTECS

UY5769250

RTECS

VQ2897000

RTECS Class

Mutagen

RTECS Class

Drug; Primary Irritant

Merck

12,8519

Beilstein/Gmelin

1699442

Beilstein/Gmelin

107971

Beilstein Reference

4-04-00-02363

Beilstein Reference

5-21-06-00328

Physical and Chemical Properties

Appearance

Clear very slight yellow liquid.

Appearance

Deliquescent crystals or powder. Has a sweetish taste.

Solubility in water

Very soluble

Melting Point

63

Boiling Point

97

Boiling Point

185

Density

0.9979 g/cm3 (20 C)

Density

1.301 g/cm3

pKa/pKb

2.44 (pKa)

Partition Coefficient

-2.8

Usage

Under investigation for the possible prevention of schizophrenic illness during the prodromal stage of the disease.

Vapor Density

3.9

Refractive Index

1.4658 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation.

Skin

Causes skin irritation. May cause cyanosis of the extremities.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Causes moderate eye irritation. May cause chemical conjunctivitis and corneal damage.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse. Keep from contact with moist air and steam.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Prolonged or repeated skin contact may cause dermatitis. Effects may be delayed.

Fire Fighting Measures

Flash Point

> 100

Flash Point

76

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation. Do not get water on spilled substances or inside containers.

Stability and Reactivity

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong acids, strong bases, strong oxidizing agents, acid chlorides.

Incompatibilities

Strong oxidizing agents, moisture.

Disposal Code

4

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information

HS Code

2922 49 95